Argüello, JoséPatel, SarjuQuintana, Julia2023-12-122023-12-122016-07-22José M Argüello, Sarju J Patel, Julia Quintana, Bacterial Cu+-ATPases: models for molecular structure–function studies, Metallomics, Volume 8, Issue 9, September 2016, Pages 906–914https://hdl.handle.net/10115/27125JMA acknowledges the NIH (R01 GM114949) for research funding.The early discovery of the human Cu(+)-ATPases and their link to Menkes and Wilson's diseases brought attention to the unique role of these transporters in copper homeostasis. The characterization of bacterial Cu(+)-ATPases has significantly furthered our understanding of the structure, selectivity and transport mechanism of these enzymes, as well as their interplay with other elements of Cu(+) distribution networks. This review focuses on the structural-functional insights that have emerged from studies of bacterial Cu(+)-ATPases at the molecular level and how these observations have contributed to drawing up a comprehensive picture of cellular copper homeostasis.enginfo:eu-repo/semantics/review10.1039/c6mt00089dinfo:eu-repo/semantics/embargoedAccess