Losada-Baltar, AndrésMausbach, Brent T.Romero-Moreno, RosaJiménez-Gonzalo, LucíaHuertas-Domingo, CristinaFernandes-Pires, José A.Barrera-Caballero, SamaraGallego-Alberto, LauraMartín-María, NataliaOlazarán, JavierMárquez-González, María2024-09-162024-09-162024-03-14Losada-Baltar A, Mausbach BT, Romero-Moreno R, et al. Longitudinal effects of ambivalent and guilt feelings on dementia family caregivers' depressive symptoms. J Am Geriatr Soc. 2024; 72(5): 1431-1441. doi:10.1111/jgs.188710002-8614 (print)1532-5415 (online)https://hdl.handle.net/10115/39556Background The world prevalence of people with dementia is increasing. Most of the care received by people with dementia is provided by family caregivers, and this prolonged activity has a significant impact on caregivers' levels of depression. Stressors and frequency of leisure are known predictors of caregivers' depressive levels. The longitudinal impact of caregivers' ambivalent and guilt feelings is unknown. Methods Participants were 177 family caregivers of relatives with dementia who were assessed three times during a 2-year period. In addition to demographic variables, psychological symptoms of the dementias, and frequency of leisure activities, caregivers' ambivalent feelings, guilt, and depressive symptoms were measured. The longitudinal association of changes in these variables with changes in caregivers' depressive symptoms over time was assessed using mixed linear models. Results Changes over time in the assessed variables predicted 48.05% of variance of changes over time in depressive symptoms. Even when variables strongly associated with increased depressive symptoms were controlled (lower caregivers' age and educational level, higher reaction to BPSD, and lower leisure activities), increases in ambivalence and guilt contributed to an increase of 9.22% of the variance of changes depressive symptoms over a 2-year period. The effects of ambivalent feelings on depression are indirect, mediated by guilt feelings. Cessation of caregiving do not seem to alter these findings. Conclusions Caregivers' ambivalent and guilt feelings are significant predictors of caregivers' mental health. Caregivers may significantly benefit from early detection of ambivalent and guilt feelings and preventive strategies targeting triggers associated with ambivalent and guilt symptomsengAttribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/article10.1111/jgs.18871info:eu-repo/semantics/openAccess