Examinando por Autor "Cifuentes, Sandra C."

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A Review of Additive Manufacturing of Biodegradable Fe and Zn Alloys for Medical Implants Using Laser Powder Bed Fusion (LPBF)
(MDPI, 2024-12-19) Limón, Irene; Bedmar, Javier; Fernández-Hernán, Juan Pablo; Multigner, Marta; Torres, Belén; Rams, Joaquín; Cifuentes, Sandra C.
This review explores the advancements in additive manufacturing (AM) of biodegradable iron (Fe) and zinc (Zn) alloys, focusing on their potential for medical implants, particularly in vascular and bone applications. Fe alloys are noted for their superior mechanical properties and biocompatibility but exhibit a slow corrosion rate, limiting their biodegradability. Strategies such as alloying with manganese (Mn) and optimizing microstructure via laser powder bed fusion (LPBF) have been employed to increase Fe’s corrosion rate and mechanical performance. Zn alloys, characterized by moderate biodegradation rates and biocompatible corrosion products, address the limitations of Fe, though their mechanical properties require improvement through alloying and microstructural refinement. LPBF has enabled the fabrication of dense and porous structures for both materials, with energy density optimization playing a critical role in achieving defect-free parts. Fe alloys exhibit higher strength and hardness, while Zn alloys offer better corrosion control and biocompatibility. In vitro and in vivo studies demonstrate promising outcomes for both materials, with Fe alloys excelling in load-bearing applications and Zn alloys in controlled degradation and vascular applications. Despite these advancements, challenges such as localized corrosion, cytotoxicity, and long-term performance require further investigation to fully harness the potential of AM-fabricated Fe and Zn biodegradable implants.
Mg as Bioabsorbable Material
(Elsevier, 2022) Multigner, Marta; Muñoz, Marta; Pulido-González, Nuria; Torres, Belén; Cifuentes, Sandra C.
Magnesium and its alloys are an outstanding option for designing temporary medical devices because of their mechanical properties and biocompatibility. However, to achieve the accurate requirements for different medical treatment, it is necessary to control their degradation process. This can be accomplished by controlling the composition, their microstructure and their surface. This work reviews the role of Mg as bioabsorbable material by remarking different strategies intended to control its degradation process: purification of magnesium, research of alloys firstly developed for industrial applications other than medical, specific design of alloys for biodegradable implants and the incorporation of magnesium as reinforcing phase of biodegradable polymeric matrix composites.