Examinando por Autor "Mausbach, Brent T."

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Bidirectional Relationship Between Insomnia and Depressive Symptoms in Family Caregivers of People with Dementia: A Longitudinal Study
(MDPI Behavioral Sciences, 2025-07-10) Jiménez-Gonzalo, Lucía; Márquez-González, María; Vara-García, Carlos; Romero-Moreno, Rosa; Olazarán Rodríguez, Javier; von Känel, Roland; Mausbach, Brent T.; Losada-Baltar, Andrés
Bidirectionality between insomnia and depression is well documented in general and clinical populations but remains under-researched in family caregivers of people with dementia. This study aimed to explore this relationship using a longitudinal design with 155 family caregivers assessed annually over three years. Data collected included sociodemographic information, health behaviors, medical data, caregiving stressors, and depressive and insomnia symptoms. Two linear mixed models were tested: Model 1 considered insomnia symptoms as the independent variable and depressive symptoms as the outcome; Model 2 considered depressive symptoms as the independent variable and insomnia symptoms as the outcome. The results showed that caregivers with more insomnia symptoms over time had significantly higher depressive symptoms, even after adjusting for covariates. Insomnia accounted for an additional 7.47% of the variance, with a total explained variance of 57.93%. Conversely, higher depressive symptoms over time were associated with increased insomnia. Depressive symptoms explained an additional 7.28% of the variance, with a total explained variance of 25.74%. These results were consistent with previous studies on non-caregiving populations, adding empirical evidence to the notion that both insomnia and depression may operate as a risk factor for the other disorder. Caregiver support interventions could improve their psychological well-being if they incorporate sleep-focused strategies.
Cognitive–Behavioral Therapy (CBT) Versus Acceptance and Commitment Therapy (ACT) for Dementia Family Caregivers With Significant Depressive Symptoms: Results of a Randomized Clinical Trial
(American Psychological Association, 2015-06-15) Losada, Andrés; Márquez-González, María; Romero-Moreno, Rosa; Mausbach, Brent T.; López, Javier; Fernández-Fernández, Virginia; Nogales-González, Celia
Objective: The differential efficacy of acceptance and commitment therapy (ACT) and cognitive–behavioral therapy (CBT) for dementia family caregivers’ is analyzed through a randomized controlled trial. Method: Participants were 135 caregivers with high depressive symptomatology who were randomly allocated to the intervention conditions or a control group (CG). Pre-, postintervention, and follow-up measurements assessed depressive symptomatology, anxiety, leisure, dysfunctional thoughts, and experiential avoidance. Results: Depression: Significant effects of interventions compared with CG were found for CBT (p < .001, d = 0.98, number needed to treat [NNT] = 3.61) and ACT (p < .001, d = 1.17, NNT = 3.53) at postintervention, but were maintained only at follow-up for CBT (p = .02, d = 0.74, NNT = 9.71). Clinically significant change was observed in 26.7% participants in CBT, 24.2% in ACT, and 0% in CG. At follow-up, 10.53% in CBT and 4% in ACT were recovered (0% CG). Anxiety: At postintervention, ACT participants showed lower anxiety than CBT participants (p < .05, d = 0.50) and CG participants (p < .01, d = 0.79, NNT = 3.86), with no effects at follow-up. At postintervention, 23.33% in CBT, 36.36% in ACT, and 6.45% in CG showed clinically significant change. At follow-up, 26.32% in CBT, 36% in ACT, and 13.64% in CG were recovered. Significant changes at postintervention were found in leisure and dysfunctional thoughts in both ACT and CBT, with changes in experiential avoidance only for ACT. Conclusion: Similar results were obtained for ACT and CBT. ACT seems to be a viable and effective treatment for dementia caregivers. (PsycInfo Database Record (c) 2020 APA, all rights reserved)
Longitudinal effects of ambivalent and guilt feelings on dementia family caregivers' depressive symptoms
(Wiley, 2024-03-14) Losada-Baltar, Andrés; Mausbach, Brent T.; Romero-Moreno, Rosa; Jiménez-Gonzalo, Lucía; Huertas-Domingo, Cristina; Fernandes-Pires, José A.; Barrera-Caballero, Samara; Gallego-Alberto, Laura; Martín-María, Natalia; Olazarán, Javier; Márquez-González, María
Background The world prevalence of people with dementia is increasing. Most of the care received by people with dementia is provided by family caregivers, and this prolonged activity has a significant impact on caregivers' levels of depression. Stressors and frequency of leisure are known predictors of caregivers' depressive levels. The longitudinal impact of caregivers' ambivalent and guilt feelings is unknown. Methods Participants were 177 family caregivers of relatives with dementia who were assessed three times during a 2-year period. In addition to demographic variables, psychological symptoms of the dementias, and frequency of leisure activities, caregivers' ambivalent feelings, guilt, and depressive symptoms were measured. The longitudinal association of changes in these variables with changes in caregivers' depressive symptoms over time was assessed using mixed linear models. Results Changes over time in the assessed variables predicted 48.05% of variance of changes over time in depressive symptoms. Even when variables strongly associated with increased depressive symptoms were controlled (lower caregivers' age and educational level, higher reaction to BPSD, and lower leisure activities), increases in ambivalence and guilt contributed to an increase of 9.22% of the variance of changes depressive symptoms over a 2-year period. The effects of ambivalent feelings on depression are indirect, mediated by guilt feelings. Cessation of caregiving do not seem to alter these findings. Conclusions Caregivers' ambivalent and guilt feelings are significant predictors of caregivers' mental health. Caregivers may significantly benefit from early detection of ambivalent and guilt feelings and preventive strategies targeting triggers associated with ambivalent and guilt symptoms