Examinando por Autor "Molina, Israel"

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Clinicoepidemiological characteristics of viral hepatitis in migrants and travellers of the +Redivi network
(Elsevier, 2019) Henriquez Camacho, Cesar; Serre, Núria; Norman , Francesca; Sánchez Montalvá, Adrián; Torrús, Diego; Goikoetxea, Ane Josune; Herrero Martínez, Juan María; Ruiz Giardín, José Manuel; Treviño, Begoña; Monge Maillo, Begoña; Molina, Israel; Rodríguez, Azucena; García, Magdalena; Lopéz Véléz, Rogelio; Pérez Molina , José A.
Background: Continuous growth of mobile populations has influenced the global epidemiology of infectious diseases, including chronic and acute viral hepatitis. Method: A prospective observational multicentre study was performed in a Spanish network of imported in- fections. Viral hepatitis cases from January 2009 to September 2017 were included. Results: Of 14,546 records, 723 (4.97%) had imported viral hepatitis, including 48 (6.64%) acute cases and 675 (93.36%) chronic cases. Of the 48 acute cases, 31 were travellers and immigrants returning from visiting friends or relatives (VFR), while 19 (61%) were acute Hepatitis A or Hepatitis B. Only 18.2% of VFR immigrants and 35% of travellers received pre-travel advice. Acute hepatitis was more frequent in VFR immigrants (AOR 2.59, CI95% 1.20–5.60) and travellers (AOR 2.83, CI95% 1.46–5.50) than immigrants. Of the 675 Chronic cases, 570 were immigrants, and 439 (77%) had chronic Hepatitis B. Chronic hepatitis was more frequent in immigrants (AOR 20.22, CI95% 11.64–35.13) and VFR immigrants (AOR 11.12, CI95% 6.20–19.94) than travellers. Conclusions: Chronic viral hepatitis was typical of immigrants, acute viral hepatitis was common among tra- vellers, and VFR immigrants had mixed risk. Improving pre-travel consultation and screening of immigrants may contribute to preventing new cases of viral hepatitis and avoiding community transmission.
Latent and active tuberculosis infections in migrants and travellers: A retrospective analysis from the Spanish +REDIVI collaborative network
(ELSEVIER, 2019-07-29) Wilkman-Jorgensen, Phillip; López-Vélez, Rogelio; Llenas-García, Jara; Treviño, Begoña; Pascual, Reyes; Molina, Israel; Dominguez, Angel; Torrús, Diego; Ruiz Giardín, José Manuel; Monge-Maillo, Begoña; Norman, Francesca; Romero, Monica; Pérez-Molina, José A.
Background: Tuberculosis (TB) is the leading cause of infectious disease mortality worldwide. We analysed active and latent TB infections (LTBI) from the Spanish Network for the Study of Imported Infectious Diseases by Travellers and Immigrants (+REDIVI). Methods: Observational, retrospective, multicentre study of TB and LTBI registered in the +REDIVI network from October 2009 to December 2016. Results: Of 1008 cases of LTBI, 884 (87.7%) were immigrants; 93 (4.5%), immigrants visiting friends and relatives (VFR); 2 (0.9%), VFR-travellers; and 29 (1.1%), travellers. Absolute (N=157 vs. N=75) and relative (12.5% vs. 5.9%) frequency decreased over the study period (p=0.003). Median time to diagnosis was 24.6 months (females 50.3 vs males 11.9; p<0.001). Of 448 TB cases, 405 (90.4%) were in immigrants; 30 (6.7%), VFR-immigrants; 6 (1.3%), VFR-travellers; and 7 (1.6%), travellers. Median time to diagnosis was 62.5 months (females 86.6 vs males 70.1; p=0.0075). There were 8 multidrug resistant TB cases and 1 extensively drug resistant case of TB, all in immigrants. Conclusion: TB was frequently diagnosed more than 5 years after arrival in Spain. Screening programmes for TB and LTBI in immigrants should be considered beyond this time point. Women showed a higher diagnostic delay for both latent and active TB.