Examinando por Autor "Perez-Redondo, Adrian"

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Access to 2-substituted 1-pyridin-3-yl-β-carboline derivatives by intramolecular radical cyclization-ring opening-SNAr substitution
(ROYAL SOC CHEMISTRY, 2019-08-08) Recio, Javier; Perez-Redondo, Adrian; Alvarez-Builla, Julio; Burgos, Carolina
A new method for the synthesis of 1-pyridin-3-yl-β-carboline derivatives involving an intramolecular radical reaction in the presence of tris(trimethylsilyl)silane and azobisisobutyronitrile (TTMSS/AIBN), via a sultam intermediate, which proceeds as a one-pot process by ring opening and SNAr substitution, is described.