Examinando por Autor "Rajasekar, Shanmuganathan"

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    Vibrational resonance in a time-delayed genetic toggle switch
    (Elsevier, 2013-02-01) Daza, Alvar; Wagemakers, Alexandre; Rajasekar, Shanmuganathan; Sanjuán, Miguel A. F.
    Biological oscillators can respond in a surprising way when they are perturbed by two external periodic forcing signals of very different frequencies. The response of the system to a low-frequency signal can be enhanced or depressed when a high-frequency signal is acting. This is what is known as vibrational resonance (VR). Here we study this phenomenon in a simple time-delayed genetic toggle switch, which is a synthetic gene-regulatory network. We have found out how the low-frequency signal changes the range of the response, while the high-frequency signal influences the amplitude at which the resonance occurs. The delay of the toggle switch has also a strong effect on the resonance since it can also induce autonomous oscillations.