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Simultaneous determination of pindolol, acebutolol and metoprolol in waters by differential-pulse voltammetry using an efficient sensor based on carbon paste electrode modified with amino-functionalized mesostructured silica

dc.contributor.authorSilva, Mariana
dc.contributor.authorMorante-Zarcero, Sonia
dc.contributor.authorPérez-Quintanilla, Damián
dc.contributor.authorSierra, Isabel
dc.date.accessioned2024-01-30T08:36:57Z
dc.date.available2024-01-30T08:36:57Z
dc.date.issued2019
dc.identifier.issn0925-4005
dc.identifier.urihttps://hdl.handle.net/10115/29169
dc.description.abstractIn this work, hexagonal mesoporous silica (HMS) and amino-functionalized HMS (HMS-NH2) were prepared and incorporated into carbon paste electrodes (CPEs) to obtain electrochemical sensors for pindolol (Pin), acebutolol (Ace) and metoprolol (Met) determination in waters by voltammetric techniques. The materials were characterized and they showed high specific surface area, large pore volume and a quasi-spherical morphology. Firstly, the electrochemical behaviour of the modified CPEs was studied by cyclic voltammetry (CV) and differential pulse voltammetry (DPV). Then, the dependence of the current intensity with the electrolyte support (type and pH) and the accumulation time was investigated to optimize the experimental conditions for simultaneous β-blockers determination by DPV. Results showed that the sensor modified with functionalized silica (NH2-HMS-CPE) exhibited strong adsorption activity, showing three well-defined peaks in the differential pulse voltammograms, that appeared at about +0.85 V (Pin), +1.11 V (Ace) and +1.45 V (Met). This fact can be attributed to the high surface area of the material, with a 3 D wormhole-like channel structure that favoured excellent pore accessibility, and the synergistic effect produced by the grafted amino groups producing hydrogen bond interactions with the oxygen atoms of the target β-blockers. The prepared sensor exhibits good reproducibility, wide linear ranges and very low detection limits (0.1, 0.046 and 0.23 μmol L−1 for Pin, Ace and Met, respectively). Moreover, the NH2-HMS-CPE was successfully applied for the simultaneous determination of Pin, Ace and Met in tap, mineral, river and sewage effluent waters with simple sample treatment (recoveries 97–112%).es
dc.language.isoenges
dc.publisherElsevieres
dc.rightsAttribution-NonCommercial-NoDerivs 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectSimultaneous determinationes
dc.subjectβ-blockerses
dc.subjectMesostructured silicaes
dc.subjectModified carbon paste electrodeses
dc.subjectDrinking and environmental waterses
dc.titleSimultaneous determination of pindolol, acebutolol and metoprolol in waters by differential-pulse voltammetry using an efficient sensor based on carbon paste electrode modified with amino-functionalized mesostructured silicaes
dc.typeinfo:eu-repo/semantics/articlees
dc.identifier.doi10.1016/j.snb.2018.12.058es
dc.rights.accessRightsinfo:eu-repo/semantics/OpenAccesses


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Attribution-NonCommercial-NoDerivs 4.0 InternationalExcept where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 4.0 International