Access to 2-substituted 1-pyridin-3-yl-β-carboline derivatives by intramolecular radical cyclization-ring opening-SNAr substitution

dc.contributor.author	Recio, Javier
dc.contributor.author	Perez-Redondo, Adrian
dc.contributor.author	Alvarez-Builla, Julio
dc.contributor.author	Burgos, Carolina
dc.date.accessioned	2024-02-01T14:28:33Z
dc.date.available	2024-02-01T14:28:33Z
dc.date.issued	2019-08-08
dc.identifier.citation	Org. Chem. Front., 2019,6, 3300-3304	es
dc.identifier.issn	2052-4129
dc.identifier.uri	https://hdl.handle.net/10115/29438
dc.description.abstract	A new method for the synthesis of 1-pyridin-3-yl-β-carboline derivatives involving an intramolecular radical reaction in the presence of tris(trimethylsilyl)silane and azobisisobutyronitrile (TTMSS/AIBN), via a sultam intermediate, which proceeds as a one-pot process by ring opening and SNAr substitution, is described.	es
dc.language.iso	eng	es
dc.publisher	ROYAL SOC CHEMISTRY	es
dc.subject	Beta-carboline derivatives	es
dc.subject	Harmine derivatives	es
dc.subject	Indoles	es
dc.subject	Pyridinium arylation	es
dc.subject	Radicalic Coupling	es
dc.title	Access to 2-substituted 1-pyridin-3-yl-β-carboline derivatives by intramolecular radical cyclization-ring opening-SNAr substitution	es
dc.type	info:eu-repo/semantics/article	es
dc.identifier.doi	10.1039/C9QO00944B	es
dc.rights.accessRights	info:eu-repo/semantics/restrictedAccess	es