| dc.contributor.author | Barba, Fructuoso | |
| dc.contributor.author | Recio, Javier | |
| dc.contributor.author | Batanero, Belen | |
| dc.date.accessioned | 2024-02-05T08:42:15Z | |
| dc.date.available | 2024-02-05T08:42:15Z | |
| dc.date.issued | 2013-04-03 | |
| dc.identifier.citation | Tetrahedron Letters 54 (2013) 1835–1838 | es |
| dc.identifier.issn | 0040-4039 | |
| dc.identifier.uri | https://hdl.handle.net/10115/29592 | |
| dc.description.abstract | The reductive amination of several carbonyl compounds (Leuckart reaction) has been performed using Nmethylformamide
and microwave technology. Under these conditions, a new mechanism is proposed via
the initial formation of an imine, followed by reduction to the amine by ‘in situ’ generated formic acid,
and further formylation of the amine. Using this methodology, the formyl derivatives of several secondary
amines were obtained in good to excellent yields. | es |
| dc.language.iso | eng | es |
| dc.publisher | ELSERVIER | es |
| dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
| dc.subject | Reductive amination | es |
| dc.subject | Leuckart reaction | es |
| dc.subject | Microwave technology | es |
| dc.subject | Redox process | es |
| dc.subject | Formylation of amines | es |
| dc.title | Microwave-assisted conversion of carbonyl compounds into formylated secondary amines: new contribution to the Leuckart reaction mechanism in N-methylformamide | es |
| dc.type | info:eu-repo/semantics/article | es |
| dc.identifier.doi | 10.1016/j.tetlet.2013.01.097 | es |
| dc.rights.accessRights | info:eu-repo/semantics/restrictedAccess | es |
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 Internacional