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Influence of Sexual Dimorphism, Aging, and Differential Cell Capture Efficiency of Blood Separation Systems on the Quality of Platelet-Rich Plasma

dc.contributor.authorTrevissón-Redondo, Bibiana
dc.contributor.authorBecerro-de-Bengoa-Vallejo, Ricardo
dc.contributor.authorSevillano, David
dc.contributor.authorGonzález, Natalia
dc.contributor.authorLosa-Iglesias, Marta Elena
dc.contributor.authorLopez-Lopez, Daniel
dc.contributor.authorAlou, Luis
dc.date.accessioned2024-10-25T07:56:01Z
dc.date.available2024-10-25T07:56:01Z
dc.date.issued2022
dc.identifier.citationTrevissón B, Becerro-de-Bengoa-Vallejo R, Sevillano D, González N, Losa-Iglesias ME, López-López D, Alou L. Influence of Sexual Dimorphism, Aging, and Differential Cell Capture Efficiency of Blood Separation Systems on the Quality of Platelet-Rich Plasma. J Clin Med. 2022 Mar 18;11(6):1683. doi: 10.3390/jcm11061683. PMID: 35330008; PMCID: PMC8953315.es
dc.identifier.urihttps://hdl.handle.net/10115/40649
dc.description.abstractFew studies have checked the impact of the hormonal/immunological dimorphism of patients on the cellular composition of platelet-rich plasma products (PRP). Whole blood (WB) from 26 volunteers was concentrated using a device previously characterized. Platelet and white blood cell (WBC) counts in WB and PRP were compared between genders, and after the population was split into pre (≤50 years)- and post (>50 years)-menopausal ages. In WB, platelet−total WBC densities were comparable in men and women. The phagocytic cell composition differed (p ≤ 0.04). After dividing by ages, phagocytic cell discrepancies were linked to women > 50 years (p ≤ 0.05), and differences emerged in lymphocyte counts (lower in >50 years groups, within and between genders, p ≤ 0.05). In PRP, densities were significantly higher, but the PRP/WB ratios varied according to blood cell (lower for phagocytic cells) and between subjects (more favorable at a lower density of a particular blood cell in WB). This “system compensatory efficiency” res
dc.language.isoenges
dc.rightsAttribution 4.0 International*
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.titleInfluence of Sexual Dimorphism, Aging, and Differential Cell Capture Efficiency of Blood Separation Systems on the Quality of Platelet-Rich Plasmaes
dc.typeinfo:eu-repo/semantics/articlees
dc.identifier.doi10.3390/jcm11061683es
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses


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Attribution 4.0 InternationalExcept where otherwise noted, this item's license is described as Attribution 4.0 International