Discriminating Bacterial Infection from Other Causes of Fever Using Body Temperature Entropy Analysis

dc.contributor.authorVargas, Borja
dc.contributor.authorCuesta-Frau, David
dc.contributor.authorGonzalez-Lopez, Paula
dc.contributor.authorFernandez-Cotarelo, Maria-Jose
dc.contributor.authorVazquez-Gomez, Oscar
dc.contributor.authorColas, Ana
dc.contributor.authorVarela, Manuel
dc.date.accessioned2024-01-29T09:00:17Z
dc.date.available2024-01-29T09:00:17Z
dc.date.issued2022-04-05
dc.description.abstractBody temperature is usually employed in clinical practice by strict binary thresholding, aiming to classify patients as having fever or not. In the last years, other approaches based on the continuous analysis of body temperature time series have emerged. These are not only based on absolute thresholds but also on patterns and temporal dynamics of these time series, thus providing promising tools for early diagnosis. The present study applies three time series entropy calculation methods (Slope Entropy, Approximate Entropy, and Sample Entropy) to body temperature records of patients with bacterial infections and other causes of fever in search of possible differences that could be exploited for automatic classification. In the comparative analysis, Slope Entropy proved to be a stable and robust method that could bring higher sensitivity to the realm of entropy tools applied in this context of clinical thermometry. This method was able to find statistically significant differences between the two classes analyzed in all experiments, with sensitivity and specificity above 70% in most cases.es
dc.identifier.citationVargas B, Cuesta-Frau D, González-López P, Fernández-Cotarelo MJ, Vázquez-Gómez Ó, Colás A, Varela M. Discriminating Bacterial Infection from Other Causes of Fever Using Body Temperature Entropy Analysis. Entropy (Basel). 2022 Apr 5;24(4):510. doi: 10.3390/e24040510. PMID: 35455174; PMCID: PMC9024484.es
dc.identifier.doi10.3390/e24040510es
dc.identifier.issn1099-4300
dc.identifier.urihttps://hdl.handle.net/10115/29119
dc.language.isoenges
dc.publisherMDPIes
dc.rightsAttribution 4.0 Internacional*
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectTime serieses
dc.subjectSlope Entropyes
dc.subjectApproximate Entropyes
dc.subjectSample Entropyes
dc.subjectClassificationes
dc.subjectFeveres
dc.titleDiscriminating Bacterial Infection from Other Causes of Fever Using Body Temperature Entropy Analysises
dc.typeinfo:eu-repo/semantics/articlees

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