Miniaturized and modified QuEChERS method with mesostructured silica as clean-up sorbent for pyrrolizidine alkaloids determination in aromatic herbs
dc.contributor.author | Izcara, Sergio | |
dc.contributor.author | Casado, Natalia | |
dc.contributor.author | Morante-Zarcero, Sonia | |
dc.contributor.author | Pérez-Quintanilla, Damián | |
dc.contributor.author | Sierra, Isabel | |
dc.date.accessioned | 2022-06-08T07:12:56Z | |
dc.date.available | 2022-06-08T07:12:56Z | |
dc.date.issued | 2022-06 | |
dc.description.abstract | This work proposes the miniaturization and modification of the QuEChERS strategy using different large pore mesostructured silicas, non-modified and modified with amino groups (NH2), as dispersive clean-up sorbents for multi-component extraction of 21 pyrrolizidine alkaloids from different aromatic herbs, combined with ultra-high performance liquid chromatography coupled to tandem mass spectrometry analysis. The procedure was miniaturized by reducing the amounts of sample (0.2 g), solvents (2 mL), clean-up sorbents (25 mg sorbent + 150 mg MgSO4) and partitioning salts (0.65 g) employed. Best results were achieved using mesostructured silicas (LP-MS-NH2) than conventional PSA. The method was validated (overall recoveries 73–105%) and applied to the analysis of 17 samples. All the samples were contaminated with PAs (average concentration 262 µg/Kg). Thyme and basil samples were the most contaminated, whereas rosemary was the least. Lasiocarpine, senecivernine N-oxide and europine N-oxide were the main PAs that contributed to their contamination. | es |
dc.identifier.citation | Sergio Izcara, Natalia Casado, Sonia Morante-Zarcero, Damián Pérez-Quintanilla, Isabel Sierra, Miniaturized and modified QuEChERS method with mesostructured silica as clean-up sorbent for pyrrolizidine alkaloids determination in aromatic herbs, Food Chemistry, Volume 380, 2022, 132189, ISSN 0308-8146, https://doi.org/10.1016/j.foodchem.2022.132189 | es |
dc.identifier.doi | 10.1016/j.foodchem.2022.132189 | es |
dc.identifier.issn | 0308-8146 | |
dc.identifier.uri | http://hdl.handle.net/10115/19469 | |
dc.language.iso | eng | es |
dc.publisher | Elsevier | es |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Pyrrolizidine alkaloids | es |
dc.subject | Aromatic herbs | es |
dc.subject | Mesostructured silicas | es |
dc.subject | µ-QuEChERS | es |
dc.subject | UHPLC-MS/MS | es |
dc.subject | Food safety | es |
dc.title | Miniaturized and modified QuEChERS method with mesostructured silica as clean-up sorbent for pyrrolizidine alkaloids determination in aromatic herbs | es |
dc.type | info:eu-repo/semantics/article | es |
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