The demography and characteristics of SARS-CoV-2 seropositive residents and staff of nursing homes for older adults in the Community of Madrid: the SeroSOS study.
dc.contributor.author | Candel, Francisco Javier | |
dc.contributor.author | Barreiro, Pablo | |
dc.contributor.author | San Roman, Jesús | |
dc.contributor.author | Carretero, Maria del Mar | |
dc.contributor.author | Sanz, Juan Carlos | |
dc.contributor.author | Pérez-Abeledo, Marta | |
dc.contributor.author | Ramos, Belen | |
dc.contributor.author | Viñuela-Prieto, Jose Manuel | |
dc.contributor.author | Canora, Jesús | |
dc.contributor.author | Martínez Peromingo, Javier | |
dc.contributor.author | Barba Martín, Raquel | |
dc.contributor.author | Zapatero, Antonio | |
dc.date.accessioned | 2024-10-29T09:21:49Z | |
dc.date.available | 2024-10-29T09:21:49Z | |
dc.date.issued | 2021-05-04 | |
dc.description.abstract | Background: Nursing homes for older adults have concentrated large numbers of severe cases and deaths for coronavirus disease 2019 (COVID-19). Methods: Point seroprevalence study of nursing homes to describe the demography and characteristic of severe acute respiratory syndrome by coronavirus 2 (SARS-CoV-2) immunoglobulin G (IgG)-positive residents and staff. Results: Clinical information and blood samples were available for 9,332 residents (mean age 86.7 ± 8.1 years, 76.4% women) and 10,614 staff (mean age 45.6 ± 11.5, 86.2% women). Up to 84.4% of residents had frailty, 84.9% co-morbidity and 69.3% cognitive impairment; 65.2% of workers were health-aides.COVID-19 seroprevalence was 55.4% (95% confidence interval (CI), 54.4-56.4) for older adults and 31.5% (30.6-32.4) for staff. In multivariable analysis, frailty of residents was related with seropositivity (odds ratio (OR): 1.19, P = 0.02). In the case of staff, age > 50 years (2.10, P < 0.001), obesity (1.19, P = 0.01), being a health-aide (1.94, P < 0.001), working in a center with high seroprevalence in residents (3.49, P < 0.001) and contact with external cases of COVID-19 (1.52, P < 0.001) were factors associated with seropositivity. Past symptoms of COVID-19 were good predictors of seropositivity for residents (5.41, P < 0.001) and staff (2.52, P < 0.001). Conclusions: Level of dependency influences risk of COVID-19 among residents. Individual and work factors, contacts outside the nursing home are associated with COVID-19 exposure in staff members. It is key to strengthen control measures to prevent the introduction of COVID-19 into care facilities from the community. | es |
dc.identifier.citation | Francisco Javier Candel, Pablo Barreiro, Jesús San Román, María del Mar Carretero, Juan Carlos Sanz, Marta Pérez-Abeledo, Belén Ramos, José Manuel Viñuela-Prieto, Jesús Canora, Francisco Javier Martínez-Peromingo, Raquel Barba, Antonio Zapatero, the investigators of the SeroSOS study, The demography and characteristics of SARS-CoV-2 seropositive residents and staff of nursing homes for older adults in the Community of Madrid: the SeroSOS study, Age and Ageing, Volume 50, Issue 4, July 2021, Pages 1038–1047, https://doi.org/10.1093/ageing/afab096 | es |
dc.identifier.doi | 10.1093/ageing/afab096 | es |
dc.identifier.issn | 00020729 | |
dc.identifier.issn | 0002-0729 (print) | |
dc.identifier.issn | 1468-2834 (online) | |
dc.identifier.uri | https://hdl.handle.net/10115/40823 | |
dc.language.iso | eng | es |
dc.publisher | Oxford University Press | es |
dc.rights.accessRights | info:eu-repo/semantics/closedAccess | es |
dc.subject | Age | es |
dc.subject | Antibodies | es |
dc.subject | Fraility | es |
dc.subject | Sars-cov-2 | es |
dc.subject | Seroepidemiologic studies | es |
dc.subject | Nursing home personnel | es |
dc.subject | Obesity | es |
dc.subject | Serological assays | es |
dc.subject | Prevalence | es |
dc.subject | Infection | es |
dc.subject | Severe acute respiratory syndrome | es |
dc.subject | Coronavirus disease 2019 | es |
dc.subject | Health care facility | es |
dc.title | The demography and characteristics of SARS-CoV-2 seropositive residents and staff of nursing homes for older adults in the Community of Madrid: the SeroSOS study. | es |
dc.type | info:eu-repo/semantics/article | es |
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