Design of spectral-spatial phase prewinding pulses and their use in small-tip fast recovery steady-state imaging
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2017-07-04
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Magnetic Resonance in Medicine
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Purpose: Spectrally selective “prewinding” radiofrequency pulses can counteract B0 inhomogeneity in steady-state sequences, but can only prephase a limited range of off- resonance. We propose spectral-spatial small-tip angle prewinding pulses that increase the off-resonance bandwidth thatcan be successfully prephased by incorporating spatially tailored excitation patterns.
Theory and Methods: We present a feasibility study to compare spectral and spectral-spatial prewinding pulses. These pulses add a prephasing term to the target magnetization pattern that aims to recover an assigned off-resonance bandwidth at the echo time. For spectral-spatial pulses, the design bandwidth is centered at the off-resonance frequency for each spatial location in a field map. We use these pulses in the small-tip fast recovery steady-state sequence, which is similar to balanced steady-state free precession. We investigate improvement of spectral-spatial pulses over spectral pulses using simulations and small-tip fast recovery scans of a gel phantom and human brain.
Results: In simulation, spectral-spatial pulses yielded lower normalized root mean squared excitation error than spectral pulses. For both experiments, the spectral-spatial pulse images are also qualitatively better (more uniform, less signal loss) than the spectral pulse images.
Conclusion: Spectral-spatial prewinding pulses can prephase over a larger range of off-resonance than their purely spectral counterparts.
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Williams, S.N., Nielsen, J.-F., Fessler, J.A. and Noll, D.C. (2018), Design of spectral-spatial phase prewinding pulses and their use in small-tip fast recovery steady-state imaging. Magn. Reson. Med., 79: 1377-1386. https://doi.org/10.1002/mrm.26794