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Mesostructured Silicas as Cation-Exchange Sorbents in Packed or Dispersive Solid Phase Extraction for the Determination of Tropane Alkaloids in Culinary Aromatics Herbs by HPLC-MS/MS

dc.contributor.authorGonzález-Gómez, Lorena
dc.contributor.authorGañán, Judith
dc.contributor.authorMorante-Zarcero, Sonia
dc.contributor.authorPérez-Quintanilla, Damián
dc.contributor.authorSierra, Isabel
dc.date.accessioned2022-06-10T06:27:25Z
dc.date.available2022-06-10T06:27:25Z
dc.date.issued2022
dc.identifier.citationGonzález-Gómez, L.; Gañán, J.; Morante-Zarcero, S.; Pérez-Quintanilla, D.; Sierra, I. Mesostructured Silicas as Cation-Exchange Sorbents in Packed or Dispersive Solid Phase Extraction for the Determination of Tropane Alkaloids in Culinary Aromatics Herbs by HPLC-MS/MS. Toxins 2022, 14, 218. https://doi.org/10.3390/toxins14030218es
dc.identifier.issn2072-6651
dc.identifier.urihttp://hdl.handle.net/10115/19511
dc.description.abstractIn this work, Hexagonal Mesoporous Silica (HMS) and Santa Barbara Amorphous-15 (SBA-15) mesostructured silicas were synthesized and functionalized with sulfonic acid groups. The materials (HMS-SO3 �� and SBA-15-SO3 ��) were evaluated as strong cation exchange sorbents for sample extract clean-up, by solid phase extraction (SPE) and dispersive solid phase extraction, to determine atropine (At) and scopolamine (Sc) in commercial culinary aromatic herbs. Under optimized conditions, 0.25 g of sample was subject to solid–liquid extraction with acidified water (pH 1.0), and good recovery percentages were achieved for At and Sc using 75 mg of HMS-SO3 �� in SPE as the clean-up stage, prior to their determination by HPLC-MS/MS. The proposed method was validated in a thyme sample showing recoveries in the range of 70–92%, good linearity (R2 > 0.999), adequate precision (RSD 14%) and low limits (MDL 0.8–2.2 g/kg and MQL 2.6–7.2 g/kg for both analytes). Sixteen aromatic herbs samples (dried thyme, basil and coriander leaves) were analysed and At was found in fourteen samples over an interval of <5–42 g/kg, whereas Sc was found in three of the sixteen samples studied (between <5–34 g/kg). The amount of At and Sc found in some analysed samples confirms the importance of setting maximum levels of At and Sc in culinary aromatic herbs.es
dc.language.isoenges
dc.publisherMDPIes
dc.rightsAtribución 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjecttropane alkaloidses
dc.subjectsolid-phase extractiones
dc.subjectdispersive solid-phase extractiones
dc.subjectstrong cation exchangees
dc.subjectmesostructured silicases
dc.subjectculinary aromatic herbses
dc.titleMesostructured Silicas as Cation-Exchange Sorbents in Packed or Dispersive Solid Phase Extraction for the Determination of Tropane Alkaloids in Culinary Aromatics Herbs by HPLC-MS/MSes
dc.typeinfo:eu-repo/semantics/articlees
dc.identifier.doi10.3390/toxins14030218es
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses


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